Endocrine Abstracts

Background: Pancreatic neuroendocrine neoplasms (NENs) are rare tumors which can sometimes be diagnosed based on symptoms of hormone excess, but, more often, they are asymptomatic, and patients frequently present with metastatic disease. While they can occur in hereditary cancer syndromes such as multiple endocrine neoplasia type 1 (MEN1), von Hippel-Lindau (VHL), or neurofibromatosis (NF1), the majority of pancreatic NENs are sporadicCase report: We rep...

Cushing’s syndrome results from an excess exposure to glucocorticoids which can result from various causes, divided into ACTH-dependent and ACTH-independent etiologies. An example of ACTH-independent causes are adrenal masses which are either benign adenomas, representing the majority of adrenal mass cases, or by malignant neoplasms. We present the case of a 52 yo woman who presented at the Emergency Department (ER) with thoracic pain and palpitations, for which several c...

Introduction: Remission after transsphenoidal surgery in patients with acromegaly is confirmed by biochemical assays of growth hormone (GH) and insulin-like growth factor-1 (IGF-1). Although their levels are usually closely correlated, discordant results of these tests have been noted, making the follow-up of acromegaly patients particularly challenging.Case report: We present the case of a 35 year old female diagnosed with acromegaly at the age of 32 ye...

Introduction: Medullary thyroid cancer is a rare neuroendocrine tumor arising from the parafollicular C cells of the thyroid gland. Calcitonin production is a characteristic feature of medullary thyroid cancer and preoperative high levels indicate an increased risk of local and distant metastatic disease. Although rare, Horner syndrome could be caused by metastatic medullary thyroid cancer. Horner syndrome usually presents with ptosis, miosis and facial anhidrosis and most of ...

Background: Quality of life (QoL) has become a useful outcome in recent studies among different specialties. In Cushing’s syndrome, elevated cortisol levels result in a decreased QoL, the cause for this impairment being multifactorial. More studies are necessary to find modifiable factors where doctors could intervene and thus improve QoL.Objective: To evaluate QoL in a group of Romanian patients with Cushing’s syndrome. Design: We performed a ...

Objectives: Post-surgical hypoparathyroidism (PoSH) is a common long-term complication after thyroid surgery. The reported median incidence rates of temporary and permanent PoSH was 27% and 1% respectively.Methods and results: We retrospectively analyzed the files of 552 patients who underwent thyroidectomy in our surgery department between 2015 and 2017 with the aim to assess the prevalence of PoSH and to identify patient and disease related factors ass...